????? ??????? ???? ??????? ??????? ?????? ?????? ???? ???????????? ???? ??? ??????? ?? ???? ???????? ????????: ?????????? ?????????.No accumulation of misoprostol acid was famous in numerous dose reports; plasma steady state was realized within two times.???? ????????? ?? ?? ????? ???? ???? ????????? ????????.???? ???? ????????? ??? ???? ??????. ??